What is AmnioBand?
What is AmnioBand?

AmnioBand is a dehydrated human placental membrane comprised of amnion and chorion. This natural covering is a bi-layer membrane that helps native tissue restoration and remodeling. Its flexible properties allow it to conform to the wound site. Essential components present within the amniotic membrane support intrinsic functions, including providing a protective and physical barrier to infection1, preventing bacteria infiltration2, providing matrix proteins3, and promoting tissue epithelization.1,2

Ideal for both acute and chronic wounds.



• Burns
• Penetrating


• Skin cancer treatments
• Scar revisions


• Venous ulcers
• Diabetic foot ulcers
• Pressure (decubitus) ulcers
• Vascular (arterial) ulcers

Easy to use, designed for wound procedures.

Ready, right out of the package. AmnioBand is hydrophilic, so you can use it in a hydrated or dehydrated state—your choice, for your procedure.

Available in multiple sizes to optimally match wound size, with little or no waste.

Stores easily. No freezing or refrigeration needed. AmnioBand needs only ambient storage and lasts up to three years on the shelf.

Flexible. Conforms to anatomy and maintains surface area contact.

Why consider placental tissue?
Why consider placental tissue?

Placental tissue have been well documented in literature, since the early 1910s, for the treatment of a variety of burns, acute and chronic wounds. It natural biologic role provides the tissue unique structural and compositional properties that facilitate and maximize the natural wound healing capacity of the host tissue. Placental tissue have been demonstrated to be safe, easy to use and beneficial in achieving fast tissue epithelialization. Four important biological properties supporting wound healing are:

Non-immunogenic so cells do not express HLA-A and -B antigens1-3
Anti-adhesive/anti-scarring to limit fibroblast activity and reduce the risk of fibrosis4-7
Anti-inflammatory to inhibit expression of inflammatory cytokines8-10
Anti-microbial to adhere closely to the wound (contains anti-microbial peptides)11-14

AmnioBand Immunogenicity

References:  Davis, 1910;  Sabella, 1913;  Douglas, 1952;  Niknejad et al. 2008;  Vo et al. 2009;  Mamede et al. 2012

Two things unique to AmnioBand
Two things unique to AmnioBand


grey-1Inherent biological components. Amnion membrane is known to contain a suite of biological matrix proteins, cytokines and growth factors that have been shown to support host tissue remodeling.1,2


The natural “cross-talk” between matrix proteins, cytokines and growth factors aid the body during tissue repair.1,2,4,5


grey-2Aseptic processing maintains and preserves the graft’s natural flexible structure and function and offers direct compatibility to the host ECM. Other processing methods are harsh and can alter or impair the healing process.* MTF does not use terminal sterilization.


References: 1. Niknejad H. et al. 2008 | 2. Mamede AC. et al. 2012 | 3. Bryant-Greenwood GD. 1998 | 4. Pastar I. et al. 2013 | 5 Higa et al. 2005 | * Data on file at MTF.

Has AmnioBand been proven to contain growth factors?
Has AmnioBand been proven to contain growth factors?

AmnioBand has been shown to retain several endogenous growth factors and cytokines that make it an ideal wound covering agent and advance the natural wound healing process.

Matrix Proteins, Cytokines and Growth Factors Facilitate in the Normal Healing Process.

Normal wound healing consists of three overlapping phases:1,2,3


References: 1. Niknejad H. et al. 2008 | 2. Mamede AC. et al. 2012 | 3. Cross & Mustoe, 200



Why is aseptic processing important?
Why is aseptic processing important?

Aseptic processing preserves AmnioBand’s natural flexible structure and function, preserving the basement membrane and matrix proteins. Terminal sterilization can alter the native matrix structure and ultimate functional performance (Mrazova H, et al 2014). Maintenance of matrix proteins and structure allows for stabilizing the inflammation phase, supporting re-epithelization and assisting in tissue remodeling.


Matrix proteins present in AmnioBand are reported to19:

•  Stabilize the inflammatory phase
•  Aid in cell migration, anchor proteins and promote cell attachment
•  Provide hydrophilic matrix to facilitate remodeling


References:  1 Clark RAF. 1993  2 Velnar T, et al. 2009  3 Teller P, et al. 2009  4 Lin ZQ, et al. 2003  5 Kieran I, et al. 2013  6 Tseng SCG, 2001  7 Solomon A, et al. 2001  8 Solomon A, et al. 2005  9 Higa et al. 2005  10 Talmi YP, et al. 1991  11 Kjaergaard N, et al. 2000  12 Stock SJ, et al. 2007 13 King AE, et al. 2007  14 Blumenfeld I, et al. 2000  15 Adler SC, et al. 2002  16 Wang L, et al. 2013  17 Schneider L, et al. 2010  18 Jiang B, et al. 2013  19 Kosir MA, et al. 2000

Ordering information.
Ordering information.

For more information contact your MTF representative:

MTFOP@mtf.org  |  1-800-433-6576